Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981958 | 0.79 | RAB9A (0.35) | THRATHRBGAARAB9AMAPT | |
| SCHEMBL6977621 | 0.78 | GAA (0.37) | THRATHRBGAARAB9AMAPT | |
| SCHEMBL8558817 | 0.77 | GAA (0.35) | THRATHRBGAARAB9AMAPT | |
| SCHEMBL8800878 | 0.76 | — | — | |
| SCHEMBL9090606 | 0.74 | GAA (0.35) | THRATHRBGAARAB9AMAPT | |
| SCHEMBL9090504 | 0.74 | GAA (0.36) | THRATHRBGAARAB9AMAPT | |
| SCHEMBL8921403 | 0.72 | RAB9A (0.40) | GAARAB9AMAPTLMNAHSD17B10 | |
| SCHEMBL9089532 | 0.71 | PARP15 (0.36) | THRATHRBGAARAB9AMAPT | |
| SCHEMBL8913251 | 0.70 | NR1I2 (0.43) | — | |
| SCHEMBL8992145 | 0.70 | GAA (0.41) | THRATHRBGAARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650419-A | Thiadiazoles and their use as antipicornaviral agents | SANOFI, S.A. | 1997-07-22 | — | — | US | disclosed |
| EP-0759755-A4 | THIADIAZOLES AND THEIR USE AS ANTIPICORNAVIRAL AGENTS | SANOFI WINTHROP INC (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0759755-A1 | Thiadiazolylalkoxyphenyl derivatives, their preparation and their use anti-picornaviral agents | SANOFI WINTHROP, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5567719-A | Thiadiazoles and their use as antipicornaviral agents | STERLING WINTHROP, INC. (US) | 1996-10-22 | — | — | US | disclosed |
| WO-1995031198-A1 | THIADIAZOLES AND THEIR USE AS ANTIPICORNAVIRAL AGENTS | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| US-5453433-A | Viricides; antiseptics to decontaminate polio, rhino and coxsackie viruses | STERLING WINTHROP INC. (US) | 1995-09-26 | — | — | US | disclosed |