Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981958 | 0.81 | RAB9A (0.35) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL6977621 | 0.80 | GAA (0.37) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL8921403 | 0.78 | RAB9A (0.40) | GAARAB9AF2LMNANPC1 | |
| SCHEMBL9089532 | 0.77 | PARP15 (0.36) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL8800873 | 0.77 | THRA (0.33) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL9090606 | 0.76 | GAA (0.35) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL8138668 | 0.76 | NR1I2 (0.54) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL8923732 | 0.76 | SCN8A (0.43) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL9090504 | 0.75 | GAA (0.36) | GAARAB9ALMNANPC1TP53 | |
| SCHEMBL8924199 | 0.74 | SCN8A (0.46) | F2KMT2AL3MBTL1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |