Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968723 | 0.86 | ALOX5 (0.54) | ALOX5HDAC6MEN1MITFKMT2A | |
| SCHEMBL8799902 | 0.79 | ALOX5 (0.53) | ALOX5HDAC6 | |
| SCHEMBL8800396 | 0.76 | ALOX5 (0.58) | ALOX5HDAC6 | |
| SCHEMBL8799350 | 0.76 | ALOX5 (0.60) | ALOX5HDAC6 | |
| SCHEMBL8967518 | 0.75 | ALOX5 (0.59) | ALOX5HDAC6 | |
| SCHEMBL8965348 | 0.75 | ALOX5 (0.57) | ALOX5HDAC6 | |
| SCHEMBL8799890 | 0.74 | ALOX5 (0.70) | ALOX5HDAC6 | |
| SCHEMBL8965126 | 0.74 | ALOX5 (0.70) | ALOX5HDAC6 | |
| SCHEMBL8800021 | 0.74 | ALOX5 (0.58) | ALOX5HDAC6 | |
| SCHEMBL8801122 | 0.73 | ALOX5 (0.60) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | disclosed |