Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.64 |
| ▸ | CCKAR | P32238 | 12/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669229 | 0.89 | CCKBR (0.57) | CCKBRCCKARLMNAPOLBMAPT | |
| SCHEMBL7544908 | 0.85 | CCKBR (0.54) | CCKBRCCKARSCN9A | |
| SCHEMBL7544921 | 0.85 | CCKBR (0.54) | CCKBRCCKARSCN9A | |
| SCHEMBL7546523 | 0.84 | CCKBR (0.52) | CCKBRCCKARSCN9A | |
| SCHEMBL7546528 | 0.84 | CCKBR (0.52) | CCKBRCCKARSCN9A | |
| SCHEMBL8669226 | 0.83 | CCKBR (0.50) | CCKBRCCKARLMNAPOLBMAPT | |
| SCHEMBL8800433 | 0.82 | CCKBR (0.46) | CCKBRCCKARSCN9A | |
| SCHEMBL7548022 | 0.81 | CCKBR (0.50) | CCKBRCCKARSCN9A | |
| SCHEMBL7548029 | 0.81 | CCKBR (0.50) | CCKBRCCKARSCN9A | |
| SCHEMBL7547976 | 0.81 | CCKBR (0.51) | CCKBRCCKARSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |