Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800802 | 0.84 | PPARG (0.45) | PPARGPPARAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8801699 | 0.83 | PPARG (0.44) | PPARGPPARAALDH1A1SMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8800525 | 0.82 | PPARG (0.43) | PPARGPPARAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8800961 | 0.79 | TSHR (0.41) | PPARGPPARAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8800504 | 0.78 | PPARG (0.43) | PPARGPPARAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9570422 | 0.78 | POLB (0.42) | PPARGPPARAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10829590 | 0.71 | PPARG (0.57) | PPARGPPARAALDH1A1NPC1RAB9A | |
| SCHEMBL1303238 | 0.70 | ALDH1A1 (0.56) | PPARGPPARAALDH1A1NPC1RAB9A | |
| SCHEMBL5217789 | 0.70 | MDM2 (0.69) | PPARGPPARAALDH1A1NPC1RAB9A | |
| SCHEMBL6177780 | 0.70 | LDHA (0.56) | PPARGPPARAALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |