Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468771 | 0.86 | IKBKB (0.59) | IKBKBMAPTUSP28KDM4EALDH1A1 | |
| SCHEMBL7846025 | 0.78 | IKBKB (0.72) | IKBKBMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5228558 | 0.77 | LIMK1 (0.54) | IKBKBMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8801032 | 0.74 | IKBKB (0.56) | IKBKBMAPTUSP28KDM4EALDH1A1 | |
| SCHEMBL22957304 | 0.73 | IKBKB (0.78) | IKBKBMAPTUSP28KDM4EALDH1A1 | |
| SCHEMBL27451465 | 0.71 | IKBKB (0.42) | IKBKBMAPTUSP28KDM4EALDH1A1 | |
| SCHEMBL22542494 | 0.69 | RAB9A (0.60) | IKBKBMAPTALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL13926047 | 0.69 | IKBKB (0.55) | IKBKBMAPTKDM4EALDH1A1KAT2B | |
| SCHEMBL25841835 | 0.68 | IKBKB (0.64) | IKBKBMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25841840 | 0.67 | IKBKB (0.58) | IKBKBMAPTUSP28KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785200-A2 | Pyridoannelated thienyl and furamyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |