Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.56 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 8/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228558 | 0.78 | LIMK1 (0.54) | IKBKBLIMK1MAPTALDH1A1NPSR1 | |
| SCHEMBL8558549 | 0.77 | IKBKB (0.71) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL8801339 | 0.74 | IKBKB (0.57) | IKBKBMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11102626 | 0.73 | IKBKB (0.64) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL19212039 | 0.72 | LIMK1 (0.77) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL29707312 | 0.72 | LIMK1 (0.77) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL16071461 | 0.72 | IKBKB (1.00) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL12562427 | 0.72 | LIMK1 (0.77) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL8801403 | 0.71 | BACE1 (0.38) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL9255600 | 0.71 | KDM4E (0.59) | IKBKBLIMK1MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785200-A2 | Pyridoannelated thienyl and furamyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |