Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 5/20 | 0.36 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802614 | 0.79 | ENPP2 (0.39) | F2CASP1ITKCYP3A4KDM4A | |
| Methyl Alcohol SCHEMBL11778530 | 0.75 | CHRM1 (0.58) | CHRM1CASP1CYP3A4ALDH1A1EPHX1 | |
| SCHEMBL8389114 | 0.74 | APP (0.45) | CHRM1CASP1MEN1KMT2AALDH1A1 | |
| SCHEMBL13845248 | 0.73 | CHRM1 (0.47) | CHRM1CASP1CYP3A4MEN1KMT2A | |
| SCHEMBL9444922 | 0.68 | FPR2 (0.43) | CHRM1CASP1CYP3A4MEN1KMT2A | |
| SCHEMBL14331820 | 0.68 | CYP3A4 (0.51) | CASP1CYP3A4ALDH1A1TSHRNPSR1 | |
| SCHEMBL8802023 | 0.68 | PPARG (0.49) | F2ITKKDM4AKDM5AKDM4C | |
| SCHEMBL7562088 | 0.67 | CYP3A4 (0.50) | CASP1CYP3A4ALDH1A1TSHRNPSR1 | |
| SCHEMBL27822152 | 0.67 | CYP3A4 (0.50) | CASP1CYP3A4ALDH1A1TSHRNPSR1 | |
| SCHEMBL7496164 | 0.67 | CYP3A4 (0.50) | CASP1CYP3A4ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |