Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800681 | 0.84 | IKBKB (0.39) | BACE1IKBKBLIMK1ALDH1A1KDM4E | |
| SCHEMBL5232001 | 0.77 | CYP2A6 (0.50) | ALDH1A1KDM4EMAPTL3MBTL1NPC1 | |
| SCHEMBL8559680 | 0.76 | CSNK2A2 (0.50) | BACE1ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL30059745 | 0.73 | MAPT (0.44) | ALDH1A1KDM4ECHRM4MAPTL3MBTL1 | |
| SCHEMBL5198179 | 0.72 | HDAC3 (0.49) | RAB9AGAA | |
| SCHEMBL8801032 | 0.71 | IKBKB (0.56) | IKBKBLIMK1ALDH1A1KDM4EMAPT | |
| SCHEMBL8563062 | 0.70 | ALDH1A1 (0.56) | IKBKBLIMK1ALDH1A1KDM4EMAPT | |
| SCHEMBL5239202 | 0.70 | CYP2A6 (0.50) | MAPTNPC1POLBRAB9AHPGD | |
| SCHEMBL16340590 | 0.70 | CHRM4 (0.46) | ALDH1A1KDM4ECHRM4MAPTTDP1 | |
| SCHEMBL20722611 | 0.69 | IKBKB (0.50) | IKBKBLIMK1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785200-A2 | Pyridoannelated thienyl and furamyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |