Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CALML3 | P27482 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP25 | Q9UHP3 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79974 | 0.88 | F10 (0.40) | MAOAMAOBGRM2 | |
| SCHEMBL8802252 | 0.85 | MAOA (0.52) | MAOAMAOBCALML3CYP3A4CYP2C19 | |
| SCHEMBL8802639 | 0.84 | MAOA (0.42) | MAOAMAOBCALML3CYP3A4CYP2C19 | |
| SCHEMBL8802069 | 0.83 | GRM2 (0.36) | MAOAMAOBGRM2 | |
| SCHEMBL78334 | 0.80 | F10 (0.60) | — | |
| SCHEMBL8563892 | 0.76 | MAOA (0.46) | MAOAMAOBCALML3USP25GRM2 | |
| SCHEMBL8801479 | 0.76 | MAOA (0.46) | MAOAMAOBCALML3USP25GRM2 | |
| SCHEMBL9047627 | 0.75 | MAOA (0.44) | MAOAMAOBCALML3CYP3A4CYP2C19 | |
| SCHEMBL10881242 | 0.71 | MAOA (0.56) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL6607536 | 0.71 | MAOA (0.56) | MAOAMAOBCALML3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785200-A2 | Pyridoannelated thienyl and furamyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |