Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256058 | 0.80 | KMT2A (0.41) | TLR8HTR2AHTR2C | |
| SCHEMBL6867355 | 0.79 | SMN1; SMN2 (0.31) | OXER1TLR8SMN1; SMN2 | |
| SCHEMBL8801877 | 0.78 | TLR8 (0.47) | CNR2TLR8SMN1; SMN2 | |
| SCHEMBL8802333 | 0.75 | TLR8 (0.49) | CNR2TLR8SMN1; SMN2 | |
| SCHEMBL2551398 | 0.74 | OXER1 (0.50) | OXER1 | |
| SCHEMBL6867352 | 0.73 | CNR2 (0.34) | OXER1CNR2TLR8SMN1; SMN2 | |
| SCHEMBL8802775 | 0.72 | CNR2 (0.36) | CNR2TLR8HTR2AHTR2C | |
| SCHEMBL14386995 | 0.72 | OXER1 (0.54) | HTR4OXER1 | |
| SCHEMBL7243871 | 0.71 | CA12 (0.44) | SMN1; SMN2 | |
| SCHEMBL8802303 | 0.70 | ALDH1A1 (0.41) | CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640080-B1 | SUBSTITUTED INDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |