Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 15/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21323507 | 0.80 | POLB (0.40) | OXER1HTR4 | |
| SCHEMBL3696937 | 0.80 | OXER1 (0.54) | OXER1 | |
| SCHEMBL24026931 | 0.78 | OXER1 (0.50) | OXER1HTTAGTR1AGTR2 | |
| SCHEMBL28223276 | 0.78 | OXER1 (0.53) | OXER1 | |
| SCHEMBL14387000 | 0.76 | OXER1 (0.54) | OXER1AGTR1AGTR2 | |
| SCHEMBL24462115 | 0.76 | OPRM1 (0.45) | OXER1HTR4 | |
| SCHEMBL3847993 | 0.75 | OXER1 (0.51) | OXER1AGTR1AGTR2 | |
| SCHEMBL15981265 | 0.74 | TSHR (0.43) | — | |
| SCHEMBL14386999 | 0.74 | AGTR1 (0.61) | OXER1AGTR1AGTR2 | |
| SCHEMBL5356702 | 0.73 | KCNH2 (0.40) | OXER1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |