Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620933 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL10479917 | 0.73 | PKM (0.47) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL29154707 | 0.71 | RXFP1 (0.49) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL14817806 | 0.70 | ALDH1A1 (0.65) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL501371 | 0.69 | HSD17B10 (0.46) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL18000415 | 0.68 | TSHR (0.41) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL8718307 | 0.66 | MAPT (0.55) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL30702637 | 0.66 | ALDH1A1 (0.70) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL2307143 | 0.66 | ALDH1A1 (0.70) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL28997213 | 0.64 | HPGD (0.47) | ALDH1A1HPGDMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681581-B1 | SUBSTITUTED FUSED PYRAZOLO COMPOUNDS AND THEIR USE AS HERBICIDES | ZENECA LTD (GB) | 1997-09-10 | — | — | EP | disclosed |
| EP-0681581-A1 | SUBSTITUTED FUSED PYRAZOLO COMPOUNDS AND THEIR USE AS HERBICIDES. | ZENECA LTD (GB) | 1995-11-15 | — | — | EP | disclosed |
| US-5430007-A | Certain herbicidal pyrazolopyridazines | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| WO-1994017062-A1 | SUBSTITUTED FUSED PYRAZOLO COMPOUNDS AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |
| US-5300478-A | Herbicides | ZENECA LIMITED (GB) | 1994-04-05 | — | — | US | disclosed |