Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123060 | 0.96 | L3MBTL1 (0.45) | L3MBTL1KDM4ENPSR1SMN1; SMN2CRHR1 | |
| SCHEMBL9124053 | 0.88 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2MAPK1HTTCRHR1 | |
| SCHEMBL11745155 | 0.86 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2MAPK1HTTCRHR1 | |
| SCHEMBL11751563 | 0.84 | PGK1 (0.46) | SMN1; SMN2HTTCRHR1ALDH1A1MAPT | |
| SCHEMBL11680191 | 0.83 | TLR7 (0.43) | L3MBTL1KDM4ENPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL9122433 | 0.82 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2ALDH1A1TLR8MAPT | |
| SCHEMBL6245357 | 0.80 | KMT2A (0.48) | L3MBTL1SMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL8872372 | 0.80 | TLR8 (0.46) | L3MBTL1KDM4ENPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL10817412 | 0.78 | L3MBTL1 (0.44) | L3MBTL1KDM4ENPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL11677186 | 0.77 | L3MBTL1 (0.37) | L3MBTL1SMN1; SMN2MAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764166-A1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | PFIZER INC. (US) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995033750-A1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | PFIZER INC. (US) | 1995-12-14 | — | — | WO | disclosed |
| US-4014677-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |