Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801700 | 0.91 | LMNA (0.51) | PTGDR2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL8801026 | 0.90 | LMNA (0.46) | THRBLMNAMEN1KMT2APOLB | |
| SCHEMBL8801498 | 0.89 | PTGDR2 (0.48) | PTGDR2TBXAS1CYP19A1 | |
| SCHEMBL8801793 | 0.89 | CYP19A1 (0.43) | THRBLMNAMEN1KMT2APOLB | |
| SCHEMBL8801646 | 0.86 | THRB (0.41) | THRBLMNAMEN1KMT2APOLB | |
| SCHEMBL8801373 | 0.86 | PTGDR2 (0.42) | PTGDR2THRBLMNAMEN1KMT2A | |
| SCHEMBL8801021 | 0.81 | LMNA (0.57) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801788 | 0.80 | LMNA (0.52) | LMNAMEN1KMT2ATBXAS1KDM4E | |
| SCHEMBL9046461 | 0.80 | LMNA (0.52) | THRBLMNAMEN1KMT2APOLB | |
| SCHEMBL8801497 | 0.78 | PTGDR2 (0.50) | PTGDR2TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |