Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 9/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.63 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | TDO2 | P48775 | 3/20 | 0.47 |
| ▸ | GAK | O14976 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802604 | 0.85 | PDGFRB (0.61) | PDGFRBPDGFRAIDO1TDO2GAK | |
| SCHEMBL8801571 | 0.83 | PDGFRB (0.58) | PDGFRBPDGFRAIDO1TDO2GAK | |
| SCHEMBL8501649 | 0.79 | PDGFRB (0.77) | PDGFRBPDGFRAGAK | |
| SCHEMBL8502613 | 0.77 | PDGFRB (1.00) | PDGFRBPDGFRA | |
| SCHEMBL12074128 | 0.77 | BRD4 (0.48) | PDGFRBPDGFRAGAKKIT | |
| SCHEMBL8801931 | 0.77 | PDGFRB (0.61) | PDGFRBPDGFRAGAKNPC1 | |
| SCHEMBL9464193 | 0.74 | CYP17A1 (0.61) | PDGFRBPDGFRAMEN1NPC1ALDH1A1 | |
| SCHEMBL28421266 | 0.74 | BRD4 (0.61) | GAKKIT | |
| SCHEMBL12074863 | 0.74 | GAK (0.48) | PDGFRBPDGFRAIDO1TDO2GAK | |
| SCHEMBL2855768 | 0.73 | PDGFRB (0.60) | PDGFRBPDGFRAMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584222-B1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE POULENC RORER INT (US) | 1997-10-08 | — | — | EP | claimed |