Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571800 | 0.87 | ALDH1A1 (0.37) | ALDH1A1HTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8800957 | 0.82 | ALDH1A1 (0.34) | ALDH1A1HTTMAPT | |
| SCHEMBL8809462 | 0.81 | HTT (0.41) | ALDH1A1HTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL23406351 | 0.73 | HTT (0.46) | ALDH1A1HTTMAPTPOLBNOS3 | |
| SCHEMBL9571798 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HTTMAPTKDM4ENOS3 | |
| SCHEMBL8801812 | 0.71 | GAA (0.48) | ALDH1A1HTTMAPT | |
| SCHEMBL22044346 | 0.70 | HTT (0.41) | ALDH1A1HTTMAPTSMN1; SMN2POLB | |
| SCHEMBL8801095 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL25389179 | 0.70 | HTT (0.42) | ALDH1A1HTTMAPTPOLBNOS3 | |
| SCHEMBL8800989 | 0.68 | ALDH1A1 (0.38) | ALDH1A1HTTMAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575056-B1 | Preparation of polycyclic dyes | BASF AG (DE) | 1997-09-17 | — | — | EP | disclosed |
| US-5362888-A | Preparation of polycyclic dyes | ZENECA LIMITED (GB) | 1994-11-08 | — | — | US | disclosed |
| EP-0575056-A1 | Preparation of polycyclic dyes | ZENECA LIMITED (GB) | 1993-12-22 | — | — | EP | disclosed |