Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811410 | 0.85 | KDM4E (0.44) | MAPTALDH1A1KDM4EPOLBGABRP | |
| SCHEMBL8801972 | 0.81 | ALDH1A1 (0.38) | HTTMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL9571800 | 0.80 | ALDH1A1 (0.37) | HTTMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL23406351 | 0.78 | HTT (0.46) | HTTMAPTALDH1A1POLBNOS3 | |
| SCHEMBL9571798 | 0.76 | ALDH1A1 (0.35) | HTTMAPTALDH1A1KDM4ENOS3 | |
| SCHEMBL8800957 | 0.75 | ALDH1A1 (0.34) | HTTMAPTALDH1A1 | |
| SCHEMBL8801812 | 0.75 | GAA (0.48) | HTTMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8809419 | 0.75 | KDM4E (0.40) | MAPTALDH1A1KDM4EPOLBCYP1A2 | |
| SCHEMBL22044346 | 0.75 | HTT (0.41) | HTTMAPTALDH1A1POLBNOS3 | |
| SCHEMBL8801095 | 0.74 | ALDH1A1 (0.41) | HTTMAPTALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4309563-A | — | — | None | — | — | JP | disclosed |
| EP-0502278-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1997-03-05 | — | — | EP | disclosed |
| US-5374724-A | Process for the preparation of substituted acetic acids | ZENECA, LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| US-5189181-A | Process for preparation 2,6-dihydrobenzo[1:26, 4:5-6]-difuran dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| JP-H04309563-A | PRODUCTION OF POLYCYCLIC DYE AND SUBSTITUTED ACETIC ACID AND SUBSTITUTED ACETIC ACID COMPOUND | IMPERIAL CHEM IND PLC <ICI> | 1992-11-02 | — | — | JP | disclosed |
| EP-0502278-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1992-09-09 | — | — | EP | disclosed |