Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056342 | 0.87 | ELANE (0.42) | ELANEMEN1KMT2AGFERHTT | |
| SCHEMBL8802009 | 0.86 | MEN1 (0.46) | ELANEMEN1KMT2AGFERHTT | |
| SCHEMBL8802865 | 0.85 | ELANE (0.44) | ELANEMEN1KMT2AGFERHTT | |
| SCHEMBL9056374 | 0.84 | ELANE (0.47) | ELANEMEN1KMT2AGFERHTT | |
| SCHEMBL8802237 | 0.83 | MEN1 (0.47) | ELANEMEN1KMT2AGFERHTT | |
| SCHEMBL9057949 | 0.83 | MEN1 (0.36) | ELANEMEN1KMT2AGFERSMN1; SMN2 | |
| SCHEMBL9056074 | 0.82 | PTPN1 (0.50) | ELANEMEN1KMT2AGFERHTT | |
| SCHEMBL8805148 | 0.82 | ELANE (0.43) | ELANEMEN1KMT2AGFERHTT | |
| SCHEMBL8390508 | 0.81 | THRB (0.46) | MEN1KMT2AGFERSMN1; SMN2MAPK1 | |
| SCHEMBL9057381 | 0.81 | ELANE (0.44) | ELANEMEN1KMT2AGFERHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |