Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801802 | 0.89 | ELANE (0.42) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8802237 | 0.89 | MEN1 (0.47) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8801975 | 0.87 | ELANE (0.44) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8804133 | 0.85 | ELANE (0.42) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL9056364 | 0.83 | KDM4E (0.43) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL8802009 | 0.83 | MEN1 (0.46) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL9057939 | 0.83 | MEN1 (0.47) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8802865 | 0.83 | ELANE (0.44) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8390532 | 0.82 | PTGES2 (0.44) | ELANEMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8388054 | 0.82 | MEN1 (0.43) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |