Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 9/20 | 0.51 |
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7830653 | 0.91 | SLC9A1 (0.58) | SLC9A1DHODHHTR7HTR2B | |
| SCHEMBL1387930 | 0.83 | KMO (0.56) | SLC9A1DHODHHTR7HTR2B | |
| SCHEMBL7827609 | 0.83 | SLC9A1 (0.55) | SLC9A1 | |
| SCHEMBL27400137 | 0.83 | SLC9A1 (0.55) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL7823537 | 0.82 | KMO (0.55) | SLC9A1DHODHHTR7HTR2B | |
| SCHEMBL27365505 | 0.82 | DHODH (0.64) | DHODH | |
| SCHEMBL12858740 | 0.82 | PARP1 (0.63) | SLC9A1HTR7HTR2B | |
| SCHEMBL9392947 | 0.79 | SLC9A1 (0.59) | SLC9A1HTR7HTR2B | |
| SCHEMBL8444457 | 0.79 | DHODH (0.40) | SLC9A1DHODH | |
| Hydrochloric Acid SCHEMBL7816188 | 0.78 | SLC9A1 (0.58) | SLC9A1HTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |