Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | UNG | P13051 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153494 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTTAS1R3TAS1R1 | |
| SCHEMBL703101 | 0.86 | TSHR (0.65) | ALDH1A1TSHRMRGPRX4MAPTTAS1R3 | |
| Hydrogen Sulfide SCHEMBL28759691 | 0.84 | TSHR (0.63) | ALDH1A1TSHRMRGPRX4MAPTTAS1R3 | |
| SCHEMBL276473 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TSHRHSD17B10TTRTDP1 | |
| SCHEMBL29955168 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TSHRHSD17B10TTRTDP1 | |
| SCHEMBL2154531 | 0.83 | CYP1A2 (0.44) | ALDH1A1TAS1R3TAS1R1TAS1R2ESR1 | |
| Ethane SCHEMBL2153562 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10TTRTDP1 | |
| SCHEMBL102841 | 0.75 | ALDH1A1 (0.52) | ALDH1A1UNGTRIM24TRIM33HSD17B10 | |
| SCHEMBL2554145 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TSHRUNGTRIM24TRIM33 | |
| SCHEMBL2562028 | 0.74 | ALDH1A1 (0.56) | ALDH1A1UNGTRIM24TRIM33PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |