SCHEMBL102841

SCHEMBL102841

Cc1cc(C=O)ccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
UNG P13051 1/20 0.46
RXRB P28702 2/20 0.45
RXRA P19793 1/20 0.44
ALDH1A3 P47895 2/20 0.43
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
PTGS2 P35354 1/20 0.42
CYP2A6 P11509 1/20 0.41
NPC1 O15118 1/20 0.41
CYP2C9 P11712 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PTPN1 P18031 2/20 0.41
NFE2L2 Q16236 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPN6 P29350 1/20 0.40
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794724 0.87 ALDH1A1 (0.41) ALDH1A1UNGRXRBRXRAALDH1A3
SCHEMBL29907874 0.86 ALDH1A1 (0.68) ALDH1A1KDM4ECYP2C9NPSR1PTPN1
SCHEMBL30589393 0.85 ALDH1A1 (0.52) ALDH1A1UNGTRIM24TRIM33RAB9A
SCHEMBL4613992 0.85 ALDH1A1 (0.52) ALDH1A1UNGTRIM24TRIM33RAB9A
SCHEMBL10893340 0.84 ALDH1A1 (0.47) ALDH1A1UNGALDH1A3TRIM24TRIM33
SCHEMBL30901985 0.84 ALDH1A1 (0.47) ALDH1A1UNGALDH1A3TRIM24TRIM33
SCHEMBL14136482 0.84 ALDH1A1 (0.43) ALDH1A1UNGALDH1A3TRIM24TRIM33
SCHEMBL940632 0.82 MCL1 (0.48) ALDH1A1RXRBRXRAPTPN1NFE2L2
SCHEMBL1800318 0.82 PARP10 (0.44) ALDH1A1ALDH1A3TRIM24TRIM33RAB9A
SCHEMBL5736343 0.81 TRIM24 (0.67) UNGRXRBRXRATRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117753217-A Anti-pollution polyamide reverse osmosis membrane containing amphoteric ions and preparation method and application thereof 万华化学集团股份有限公司 2024-03-26 CN claimed
CN-112707809-B Method for preparing oxazoline insecticide fluorine Lei Lana intermediate 丽珠集团新北江制药股份有限公司 2023-08-29 CN claimed
CN-112707809-A Method for preparing oxazoline insecticide frainer intermediate 丽珠集团新北江制药股份有限公司 2021-04-27 CN claimed
US-20140031562-A1 Method for Forming Allylic Alcohols THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) 2014-01-30 US claimed
WO-2010025366-A2 METHOD FOR FORMING ALLYLIC ALCOHOLS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-03-04 WO claimed
EP-1773843-A4 SMALL MOLECULE THIENOPYRIMIDINE-BASED PROTEIN TYROSINE KINASE INHIBITORS UNIV TEXAS (US) 2009-06-03 EP claimed
WO-2008044895-A1 THE PROCESS OF ISOLATING METHYL-4-FORMYLBENZOATE AND DIMETHYLTEREPHTALATE SK ENERGY CO., LTD. (KR) 2008-04-17 WO claimed
EP-1773843-A1 SMALL MOLECULE THIENOPYRIMIDINE-BASED PROTEIN TYROSINE KINASE INHIBITORS The Board of Regents of The University of Texas System (US) 2007-04-18 EP claimed
WO-2006014404-A1 SMALL MOLECULE THIENOPYRIMIDINE-BASED PROTEIN TYROSINE KINASE INHIBITORS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-02-09 WO claimed
US-20060004002-A1 Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2006-01-05 US claimed
WO-2003072534-A1 METHOD FOR PREPARING P-AMINOBENZOIC ACID SK CHEMICALS CO., LTD. (KR) 2003-09-04 WO claimed
EP-0813515-B1 Process for the preparation of esters of stilbenedicarbonic acid and process for the preparation of p-(chloromethyl)-benzoic acid EASTMAN CHEM CO (US) 2000-06-28 EP claimed
EP-0813516-B1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEM CO (US) 1999-12-01 EP claimed
US-12638399-B2 Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these ARCHER-DANIELS-MIDLAND COMPANY (US) 2026-05-26 US disclosed
EP-4171538-B1 SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS UNIV ILLINOIS (US) 2026-04-29 EP disclosed
US-20260070879-A1 ISOXAZOLINE DERIVATIVES ELANCO TIERGESUNDHEIT AG (CH) 2026-03-12 US disclosed
EP-0161939-B1 ARYLHYDROXAMATES E.R. Squibb & Sons, Inc. (US) 1993-07-21 EP disclosed
US-4783529-A Rapid synthesis of radiolabeled porphyrin complexes for medical application RESEARCH CORPORATION TECHNOLOGIES (US) 1988-11-08 US disclosed
US-4607053-A L2POXYGENASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1986-08-19 US disclosed
EP-0161939-A2 Arylhydroxamates E.R. Squibb & Sons, Inc. (US) 1985-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004002-A1 Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors SRC, LCK, FYN ALDH1A1 4583/4885UNG 1913/4885RXRB 4299/4885
US-20140031562-A1 Method for Forming Allylic Alcohols ADH1A, ADH1C, ADH5 ALDH1A1 21/4885UNG 538/4885RXRB 2201/4885
US-20260070879-A1 ISOXAZOLINE DERIVATIVES CHRM1, CBR3, AFF1 ALDH1A1 972/4885UNG 4827/4885RXRB 1365/4885
US-12638399-B2 Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these FTO, AOC1, AOC2 ALDH1A1 49/4885UNG 298/4885RXRB 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.