Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 10/20 | 0.70 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.70 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.70 |
| ▸ | CHRNA5 | P30532 | 3/20 | 0.51 |
| ▸ | HPGDS | O60760 | 4/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.45 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620719 | 0.78 | ALDH1A1 (0.46) | CHRNB2CHRNA4CHRNA7HPGDSALDH1A1 | |
| SCHEMBL620720 | 0.78 | ALDH1A1 (0.46) | CHRNB2CHRNA4CHRNA7HPGDSALDH1A1 | |
| SCHEMBL545163 | 0.76 | MAOB (0.65) | HPGDSALDH1A1F2GLAHPGD | |
| SCHEMBL20799517 | 0.73 | ALDH1A1 (0.62) | HPGDSALDH1A1F2GLAHPGD | |
| SCHEMBL622650 | 0.71 | HPGDS (0.49) | HPGDS | |
| SCHEMBL622649 | 0.71 | HPGDS (0.49) | HPGDS | |
| SCHEMBL61795 | 0.69 | ALDH1A1 (0.64) | HPGDSALDH1A1F2GLAHPGD | |
| SCHEMBL4407431 | 0.69 | ALDH1A1 (0.68) | HPGDSALDH1A1F2GLAHPGD | |
| SCHEMBL1353255 | 0.69 | HPGDS (0.63) | HPGDSALDH1A1F2GLAHPGD | |
| SCHEMBL8802477 | 0.69 | HPGDS (0.45) | HPGDSALDH1A1F2GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499995-B1 | Piperidine derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5246945-A | 5-hydroxytryptamine antagonist for nervous system disorders | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0499995-A2 | Piperidine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |