Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 3/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ILF3 | Q12906 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051134 | 0.95 | MAOA (0.54) | MAOAMAOBCDC25ACDC25BGSTP1 | |
| SCHEMBL4279434 | 0.93 | MAOA (0.43) | MAOAMAOBCDC25ACDC25BGSTP1 | |
| SCHEMBL27935063 | 0.91 | MAOA (0.50) | MAOAMAOBCDC25ACDC25BGSTP1 | |
| SCHEMBL27916612 | 0.91 | MAOA (0.50) | MAOAMAOBCDC25ACDC25BGSTP1 | |
| SCHEMBL11864498 | 0.81 | IDO1 (0.46) | MAOAMAOBCDC25ACDC25BGSTP1 | |
| SCHEMBL30130196 | 0.80 | MEN1 (0.56) | MAOACDC25BGSTP1ELANEILF3 | |
| SCHEMBL29364188 | 0.80 | MEN1 (0.56) | MAOACDC25BGSTP1ELANEILF3 | |
| SCHEMBL354514 | 0.80 | MEN1 (0.56) | MAOACDC25BGSTP1ELANEILF3 | |
| SCHEMBL9429592 | 0.79 | ELANE (0.50) | CDC25BGSTP1ELANEILF3GAPDH | |
| SCHEMBL16144676 | 0.78 | MEN1 (0.53) | MAOACDC25BGSTP1ELANEILF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800504-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |