Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4269080 | 0.84 | MAPT (0.49) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL8594839 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL3469591 | 0.84 | MAPT (0.49) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL7801786 | 0.81 | ALDH1A1 (0.45) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4618823 | 0.81 | MAPT (0.47) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL3986231 | 0.81 | MAPT (0.47) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL9542124 | 0.80 | MAPT (0.42) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL4413021 | 0.79 | MAPT (0.44) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL8663859 | 0.79 | MAPT (0.47) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL1026028 | 0.78 | MAPT (0.41) | MAPTALDH1A1GAAMDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772593-A1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-05-14 | — | — | EP | disclosed |