Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469591 | 0.90 | MAPT (0.49) | MAPTALDH1A1GAAPKMMDM2 | |
| SCHEMBL30518402 | 0.83 | PKM (0.40) | MAPTPKM | |
| SCHEMBL8663859 | 0.82 | MAPT (0.47) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL8803147 | 0.81 | MAPT (0.46) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL8594839 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL4269080 | 0.79 | MAPT (0.49) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL7801786 | 0.77 | ALDH1A1 (0.45) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4618823 | 0.77 | MAPT (0.47) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL9542124 | 0.75 | MAPT (0.42) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL4413021 | 0.75 | MAPT (0.44) | MAPTALDH1A1GAAMDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058387-A2 | OLIGOMER-NITROIMIDAZOLE ANTI-INFECTIVE CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |