Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.47 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | ATG7 | O95352 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804074 | 1.00 | ADORA3 (0.58) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL13479946 | 0.83 | ADORA3 (0.64) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL19121006 | 0.83 | ADORA3 (0.64) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL658005 | 0.83 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL5982454 | 0.83 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL658006 | 0.83 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL5982465 | 0.83 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL24420487 | 0.82 | ADORA3 (0.66) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL6302264 | 0.82 | ADORA3 (0.66) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL18952838 | 0.82 | ADORA3 (0.66) | ADORA3ADORA2AHSPA5HSPA8RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753525-A1 | CYCLIC NUCLEOTIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-01-15 | — | — | EP | disclosed |