Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804756 | 0.90 | KMT2A (0.52) | MEN1KMT2AKDM4ESMN1; SMN2MAOB | |
| SCHEMBL8803850 | 0.84 | KDM4E (0.48) | MEN1KMT2AKDM4EMAOBMAOA | |
| SCHEMBL8804828 | 0.84 | FAAH (0.56) | CCR3MEN1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL8804549 | 0.82 | ALDH1A1 (0.46) | CYP2C19MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8804366 | 0.82 | MAOB (0.43) | MEN1KMT2AKDM4ESMN1; SMN2MAOB | |
| SCHEMBL8804771 | 0.82 | SMN1; SMN2 (0.46) | MEN1KMT2AKDM4ESMN1; SMN2MAOB | |
| SCHEMBL8803216 | 0.82 | KMT2A (0.50) | CCR3CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL8804730 | 0.81 | MEN1 (0.43) | MEN1KMT2AKDM4ESMN1; SMN2MAOB | |
| SCHEMBL8804511 | 0.81 | MAPT (0.58) | CYP3A4CYP2C19MEN1KMT2AKDM4E | |
| SCHEMBL8805530 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AKDM4ESMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |