Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.54 |
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | UBE2M | P61081 | 3/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806531 | 0.93 | MAOB (0.57) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8805910 | 0.88 | MAOB (0.57) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8812384 | 0.86 | UBE2M (0.54) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8804158 | 0.86 | MAOB (0.54) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8804174 | 0.86 | MAOB (0.54) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8803795 | 0.82 | MAOB (0.50) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8805057 | 0.81 | MAOB (0.69) | MAOBMAOAACHEBCHEUBE2M | |
| SCHEMBL8805548 | 0.81 | UBE2M (0.39) | MAOBMAOAUBE2MDCUN1D1THRB | |
| SCHEMBL8804627 | 0.80 | MAOB (0.49) | MAOBMAOAACHEBCHE | |
| SCHEMBL8805523 | 0.80 | DCUN1D1 (0.43) | MAOBMAOALMNAUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |