Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.54 |
| ▸ | MAOA | P21397 | 9/20 | 0.54 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805910 | 0.89 | MAOB (0.57) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8806531 | 0.87 | MAOB (0.57) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8804158 | 0.87 | MAOB (0.54) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8804178 | 0.86 | MAOB (0.54) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8803795 | 0.83 | MAOB (0.50) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8812384 | 0.82 | UBE2M (0.54) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8805057 | 0.82 | MAOB (0.69) | MAOBMAOAACHEBCHEKDM4E | |
| SCHEMBL8804627 | 0.81 | MAOB (0.49) | MAOBMAOAACHEBCHEMEN1 | |
| SCHEMBL8805409 | 0.80 | MAOB (0.55) | MAOBMAOAACHEBCHELMNA | |
| SCHEMBL8803034 | 0.79 | MAOB (0.61) | MAOBMAOAACHEBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |