Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50947 | 0.98 | LMNA (0.40) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL212936 | 0.93 | — | — | |
| SCHEMBL20924775 | 0.85 | LMNA (0.39) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL17526910 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL1556424 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL17526803 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL27746130 | 0.83 | TSHR (0.35) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL346677 | 0.82 | — | — | |
| SCHEMBL7919814 | 0.82 | LMNA (0.56) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL17527025 | 0.82 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679152-B1 | ANTI-ANDROGENIC CYCLO AND BICYCLO ALKENES | COSMOS PHARM CORP (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0679152-A1 | ANTI-ANDROGENIC CYCLO AND BICYCLO ALKENES. | LAFOR LAB LTD (US) | 1995-11-02 | — | — | EP | disclosed |
| WO-1994015900-A1 | ANTI-ANDROGENIC CYCLO AND BICYCLO ALKENES | LAFOR LABORATORIES LIMITED (US) | 1994-07-21 | — | — | WO | disclosed |
| US-5264619-A | Anti-androgenic cyclo and bicyclo alkenes | LAFOR LABORATORIES LIMITED (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0107733-A4 | CYCLOALIPHATIC PHARMACEUTICAL COMPOUNDS. | CBD CORP (US) | 1984-09-13 | — | — | EP | disclosed |
| EP-0107733-A1 | CYCLOALIPHATIC PHARMACEUTICAL COMPOUNDS. | CBD CORP (US) | 1984-05-09 | — | — | EP | disclosed |
| WO-1983004019-A1 | CYCLOALIPHATIC PHARMACEUTICAL COMPOUNDS | CBD CORPORATION (US) | 1983-11-24 | — | — | WO | disclosed |