Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.63 |
| ▸ | HTR7 | P34969 | 5/20 | 0.45 |
| ▸ | HTR2B | P41595 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803284 | 0.99 | SLC9A1 (0.65) | SLC9A1HTR7HTR2BDRD2ADRA1D | |
| SCHEMBL3341824 | 0.83 | ALDH1A1 (0.55) | — | |
| SCHEMBL8804089 | 0.83 | SLC9A1 (0.60) | SLC9A1HTR7HTR2BDRD2ADRA1D | |
| SCHEMBL8804714 | 0.82 | SLC9A1 (0.62) | SLC9A1HTR7HTR2BDRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL9402429 | 0.79 | SLC9A1 (0.65) | SLC9A1HTR7HTR2B | |
| SCHEMBL23792954 | 0.79 | GAA (0.60) | — | |
| SCHEMBL7825554 | 0.78 | SLC9A1 (0.55) | SLC9A1HTR7HTR2BDRD2ADRA1D | |
| SCHEMBL29357040 | 0.78 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL3906519 | 0.78 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL15392283 | 0.77 | GAA (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556672-B1 | Amino-substituted benzoylguanidines with antiarrhythmic properties | HOECHST AG (DE) | 1997-08-06 | — | — | EP | claimed |
| US-5364868-A | Amino-substituted benzoylguanidines, process for their preparation, their use as a medicament and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | claimed |
| CN-1075960-A | Amino benzoyl guanidine, its preparation method that replaces is as the purposes and the medicament that contains it of medicine | HOECHST AG (DE) | 1993-09-08 | — | — | CN | claimed |
| EP-0556672-A1 | Amino-substituted benzoylguanidines with antiarrhythmic properties | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | claimed |
| CN-1036267-C | Amino-subst.-benzoyl guanidines, a process for production thereof, use as drug thereof and drug containing it | HOECHST AG (DE) | 1997-10-29 | — | — | CN | disclosed |
| EP-0556672-B1 | Amino-substituted benzoylguanidines with antiarrhythmic properties | HOECHST AG (DE) | 1997-08-06 | — | — | EP | disclosed |
| US-5364868-A | Amino-substituted benzoylguanidines, process for their preparation, their use as a medicament and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| CN-1075960-A | Amino benzoyl guanidine, its preparation method that replaces is as the purposes and the medicament that contains it of medicine | HOECHST AG (DE) | 1993-09-08 | — | — | CN | disclosed |
| EP-0556672-A1 | Amino-substituted benzoylguanidines with antiarrhythmic properties | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | disclosed |