Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804058 | 0.88 | KMT2A (0.47) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3262858 | 0.85 | MEN1 (0.45) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2514751 | 0.79 | TAAR1 (0.49) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28985490 | 0.79 | ALOX5 (0.42) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL411370 | 0.79 | TAAR1 (0.45) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL19582798 | 0.79 | TAAR1 (0.45) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14524332 | 0.79 | ALOX5 (0.46) | ALOX5KMT2AMEN1MAOBSLC6A2 | |
| SCHEMBL8803172 | 0.79 | DRD4 (0.50) | DRD4TAAR1ALOX5KMT2AMEN1 | |
| SCHEMBL17593201 | 0.79 | TAAR1 (0.45) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8804536 | 0.79 | TAAR1 (0.45) | TAAR1ALOX5KMT2AMEN1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492474-B1 | 1,3-Dioxolane derivatives as cholesterol-lowering agents | SYNTEX INC (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5466838-A | Catalytic reaction of olefin with oxygen in the presence of aldehyde | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0540009-B1 | Process for producing epoxides | SUMITOMO CHEMICAL CO (JP) | 1995-08-30 | — | — | EP | disclosed |
| US-5367087-A | Process for producing epoxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0540009-A1 | Process for producing epoxides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5158949-A | 1,3-DIOXOLANE DERIVATIVES AS CHOLESTEROL-LOWERING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0492474-A1 | 1,3-Dioxolane derivatives as cholesterol-lowering agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-4272545-A | FUNGICIDES, BACTERICIDE, ANTIPROTOZOA, SPERMATOCIDE | SYNTEX (U.S.A.) INC. (US) | 1981-06-09 | — | — | US | disclosed |