Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804058 | 0.93 | KMT2A (0.47) | MEN1KMT2AIGF1RALOX15KCNH2 | |
| SCHEMBL8804583 | 0.85 | DRD4 (0.51) | MEN1KMT2AALDH1A1DRD4CYP1A2 | |
| SCHEMBL8070541 | 0.81 | MEN1 (0.65) | MEN1KMT2AALDH1A1TAAR1MGLL | |
| SCHEMBL10487984 | 0.81 | MEN1 (0.65) | MEN1KMT2AALDH1A1TAAR1MGLL | |
| SCHEMBL13423741 | 0.81 | MEN1 (0.65) | MEN1KMT2AALDH1A1TAAR1MGLL | |
| SCHEMBL9136546 | 0.81 | MEN1 (0.65) | MEN1KMT2AALDH1A1TAAR1MGLL | |
| SCHEMBL13839941 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1ENPP2MGLL | |
| SCHEMBL51135 | 0.79 | MEN1 (0.67) | MEN1KMT2ATAAR1MGLL | |
| SCHEMBL28966782 | 0.78 | IGF1R (0.61) | IGF1RALOX15KCNH2HDAC3HDAC4 | |
| SCHEMBL1115439 | 0.78 | IGF1R (0.61) | IGF1RALOX15KCNH2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168176-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | FASGEN LLC (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100120901-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | FASGEN,INC (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100029761-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | FAS SECURED CREDITORS HOLDCO, LLC | 2010-02-04 | — | — | US | disclosed |
| US-20100029752-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | FAS SECURED CREDITORS HOLDCO, LLC | 2010-02-04 | — | — | US | disclosed |
| US-20060241177-A1 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same | FAS SECURED CREDITORS HOLDCO, LLC | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241177-A1 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same | CPT1B, CPT1A, CRAT | MEN1 2433/4885KMT2A 3758/4885IGF1R 348/4885 |
| US-20100029752-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | CYP3A7, DHCR7, CYP2A7 | MEN1 2293/4885KMT2A 4580/4885IGF1R 1137/4885 |
| US-20100120901-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | CPT1A, CPT1B, CPT2 | MEN1 2374/4885KMT2A 4379/4885IGF1R 310/4885 |
| US-20100168176-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | AOC3, CYP2B6, CBR3 | MEN1 2061/4885KMT2A 3678/4885IGF1R 679/4885 |
| US-20100029761-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | NR1H4, CYP3A4, CYP4A11 | MEN1 2674/4885KMT2A 3143/4885IGF1R 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.