Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | GFER | P55789 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353029 | 0.85 | ALDH1A1 (0.83) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL1509619 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL25541644 | 0.82 | POLB (0.58) | ALDH1A1KDM4EMEN1KMT2AACHE | |
| SCHEMBL23179687 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL8803675 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL3614984 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AACHEL3MBTL1 | |
| SCHEMBL8099793 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AACHEL3MBTL1 | |
| SCHEMBL23179683 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4EGFERMEN1KMT2A | |
| SCHEMBL1021686 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4EMEN1KMT2AACHE | |
| SCHEMBL3181878 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |