Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 18/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804622 | 0.82 | P2RY1 (0.54) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL8804204 | 0.80 | NPC1 (0.43) | EPHX2MAPK1LMNA | |
| SCHEMBL8805284 | 0.79 | CFD (0.48) | MAPK1LMNA | |
| SCHEMBL8804785 | 0.79 | P2RY1 (0.47) | LMNA | |
| SCHEMBL8806034 | 0.78 | KMT2A (0.59) | EPHX2EPHX1LMNA | |
| SCHEMBL8803889 | 0.78 | EPHX2 (0.54) | EPHX2MAPK1SIGMAR1 | |
| SCHEMBL8803890 | 0.78 | EPHX2 (0.54) | EPHX2MAPK1SIGMAR1 | |
| SCHEMBL8803651 | 0.78 | KMT2A (0.61) | EPHX2EPHX1LMNA | |
| SCHEMBL8805456 | 0.78 | KMT2A (0.61) | EPHX2EPHX1LMNA | |
| SCHEMBL8804783 | 0.78 | KMT2A (0.61) | EPHX2EPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |