Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 17/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804609 | 0.80 | EPHX2 (0.54) | EPHX2LMNAMAPK1 | |
| SCHEMBL8804151 | 0.74 | RAB9A (0.42) | NPC1RAB9APOLB | |
| SCHEMBL8805166 | 0.72 | SSTR4 (0.35) | POLBSMN1; SMN2LMNA | |
| SCHEMBL8803219 | 0.72 | MAOB (0.63) | POLB | |
| SCHEMBL8803979 | 0.71 | SOAT2 (0.49) | — | |
| Hydrochloric Acid SCHEMBL8804469 | 0.71 | MAOB (0.62) | POLB | |
| SCHEMBL8806812 | 0.71 | GAA (0.36) | SMN1; SMN2LMNA | |
| SCHEMBL8804351 | 0.70 | GAA (0.33) | — | |
| SCHEMBL8804354 | 0.70 | GAA (0.33) | — | |
| SCHEMBL4347622 | 0.70 | EPHX2 (0.60) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |