Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798232 | 0.90 | EDNRB (0.52) | EDNRBSERPINE1 | |
| SCHEMBL8578797 | 0.86 | EDNRB (0.67) | EDNRB | |
| SCHEMBL8575986 | 0.83 | EDNRB (0.65) | EDNRB | |
| SCHEMBL8798447 | 0.76 | EDNRB (0.53) | EDNRB | |
| SCHEMBL8804652 | 0.76 | EDNRB (1.00) | EDNRB | |
| SCHEMBL8798914 | 0.74 | EDNRB (0.53) | EDNRB | |
| SCHEMBL8578669 | 0.74 | EDNRB (1.00) | EDNRB | |
| SCHEMBL27482311 | 0.69 | MAPT (0.57) | EDNRBSERPINE1 | |
| SCHEMBL8553063 | 0.68 | EDNRB (0.54) | EDNRB | |
| SCHEMBL795880 | 0.68 | EDNRB (1.00) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731321-A | Endothelin receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-24 | — | — | US | disclosed |
| EP-0757039-A1 | Endothelin receptor antagonists | MERCK PATENT GmbH (DE) | 1997-02-05 | — | — | EP | disclosed |