Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805417 | 0.93 | CYP11B1 (0.42) | CYP11B1CYP11B2AGERPOLBCTDSP1 | |
| SCHEMBL11284437 | 0.81 | CYP11B1 (0.52) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL11277864 | 0.81 | CYP11B1 (0.48) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL8803353 | 0.81 | CYP19A1 (0.56) | CYP11B1CYP11B2AGERTDP1CYP19A1 | |
| SCHEMBL11273980 | 0.81 | CYP11B1 (0.47) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL11286350 | 0.80 | CYP11B1 (0.45) | CYP11B1CYP11B2POLBCYP19A1 | |
| SCHEMBL11270205 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL11285968 | 0.79 | CYP11B1 (0.44) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL11275707 | 0.78 | ALDH1A1 (0.48) | CYP11B1CYP11B2TDP1CYP19A1 | |
| SCHEMBL11279504 | 0.78 | IDO1 (0.45) | CYP11B1CYP11B2TDP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492474-B1 | 1,3-Dioxolane derivatives as cholesterol-lowering agents | SYNTEX INC (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5158949-A | 1,3-DIOXOLANE DERIVATIVES AS CHOLESTEROL-LOWERING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0492474-A1 | 1,3-Dioxolane derivatives as cholesterol-lowering agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-4518607-A | FUNGICIDES, BACXTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1985-05-21 | — | — | US | disclosed |
| US-4078071-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-03-07 | — | — | US | disclosed |