Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806812 | 0.88 | GAA (0.36) | GAAKMT2APTGES2HTTALDH1A1 | |
| SCHEMBL8803886 | 0.82 | TRPV1 (0.33) | GAAKMT2APTGES2HTTALDH1A1 | |
| SCHEMBL8804215 | 0.81 | TRPV1 (0.40) | SSTR4GAAPOLBKMT2AHTT | |
| SCHEMBL8805179 | 0.81 | OPRL1 (0.35) | GAAKMT2APTGES2LMNAF2R | |
| SCHEMBL8804204 | 0.72 | NPC1 (0.43) | POLBLMNASMN1; SMN2 | |
| SCHEMBL8803219 | 0.71 | MAOB (0.63) | POLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8804469 | 0.70 | MAOB (0.62) | POLBKMT2AALDH1A1 | |
| SCHEMBL8804959 | 0.69 | MAOB (0.59) | POLBKMT2AALDH1A1 | |
| SCHEMBL8804984 | 0.69 | GAA (0.38) | GAAKMT2AALDH1A1LMNA | |
| SCHEMBL8806503 | 0.69 | GAA (0.39) | GAAPOLBKMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |