Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | EEF2K | O00418 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803850 | 0.89 | KDM4E (0.48) | MAOBMAOAACHEKDM4EALDH1A1 | |
| SCHEMBL8805195 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1LMNAMAPK1FAAH | |
| SCHEMBL8805530 | 0.87 | ALDH1A1 (0.43) | MAOBMAOAACHEKDM4EALDH1A1 | |
| SCHEMBL8804511 | 0.87 | MAPT (0.58) | MAOBMAOAACHEKDM4EUSP2 | |
| SCHEMBL8804756 | 0.87 | KMT2A (0.52) | MAOBMAOAACHEKDM4EALDH1A1 | |
| SCHEMBL8804730 | 0.86 | MEN1 (0.43) | MAOBMAOAACHEKDM4EUSP2 | |
| SCHEMBL8804549 | 0.85 | ALDH1A1 (0.46) | MAOBMAOAKDM4EALDH1A1LMNA | |
| SCHEMBL8804828 | 0.85 | FAAH (0.56) | MAOBMAOAACHELMNAFAAH | |
| SCHEMBL8805057 | 0.83 | MAOB (0.69) | MAOBMAOAACHEKDM4EALDH1A1 | |
| SCHEMBL8804114 | 0.83 | GAA (0.43) | MAOBMAOAACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |