⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245717 | 0.69 | — | — | |
| SCHEMBL3149601 | 0.69 | — | — | |
| SCHEMBL3136394 | 0.69 | — | — | |
| SCHEMBL336278 | 0.68 | — | — | |
| SCHEMBL9349777 | 0.67 | — | — | |
| SCHEMBL3143489 | 0.65 | — | — | |
| SCHEMBL6206985 | 0.65 | — | — | |
| SCHEMBL1002690 | 0.65 | — | — | |
| SCHEMBL26039174 | 0.65 | — | — | |
| SCHEMBL2909785 | 0.64 | PDK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559690-B1 | 8-ENE-19, 11 beta-BRIDGED STEROIDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | SCHERING AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0559690-A1 | 8-ENE-19, 11-g(b)-BRIDGED STEROIDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM. | SCHERING AG (DE) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009618-A1 | 8-ENE-19, 11β-BRIDGED STEROIDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1992-06-11 | — | — | WO | disclosed |
| EP-0283428-B1 | 19,11-BETA-BRIDGED STEROIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-10-30 | — | — | EP | disclosed |
| EP-0283428-A1 | 19,11-Beta-bridged steroids, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-09-21 | — | — | EP | disclosed |