Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202085 | 1.00 | HCAR2 (0.56) | HCAR2ALDH1A1HTTMETNPC1 | |
| SCHEMBL8806009 | 0.93 | HCAR2 (0.68) | HCAR2ALDH1A1HTTMETNPC1 | |
| SCHEMBL8805999 | 0.93 | HCAR2 (0.68) | HCAR2ALDH1A1HTTMETNPC1 | |
| SCHEMBL10807885 | 0.93 | HCAR2 (0.68) | HCAR2ALDH1A1HTTMETNPC1 | |
| SCHEMBL14936817 | 0.91 | ALDH1A1 (0.51) | HCAR2ALDH1A1HTTMETNPC1 | |
| SCHEMBL14936820 | 0.91 | ALDH1A1 (0.51) | HCAR2ALDH1A1HTTMETNPC1 | |
| SCHEMBL19333588 | 0.89 | MET (0.51) | HCAR2ALDH1A1HTTMETNPC1 | |
| SCHEMBL10399767 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HTTNPC1POLBRAB9A | |
| SCHEMBL8016679 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HTTNPC1POLBRAB9A | |
| SCHEMBL22615627 | 0.87 | ALDH1A1 (0.48) | HCAR2ALDH1A1HTTMETNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232966-B1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1997-10-08 | — | — | EP | disclosed |