Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806996 | 0.90 | ABCB1 (0.38) | ABCB1ABCG2MAPTTP53RXFP1 | |
| SCHEMBL8807018 | 0.90 | MAPT (0.42) | SLC2A1ABCB1ABCG2MAPTTP53 | |
| SCHEMBL8807995 | 0.90 | MAOA (0.39) | ABCG2MAPTTP53RXFP1MEN1 | |
| SCHEMBL8807360 | 0.88 | ABCB1 (0.39) | ABCB1ABCG2MAPTTP53RXFP1 | |
| SCHEMBL8808392 | 0.87 | MAPT (0.45) | SLC2A1ABCB1ABCG2MAPTTP53 | |
| SCHEMBL8806947 | 0.85 | ABCB1 (0.39) | ABCB1ABCG2MAPTTP53RXFP1 | |
| SCHEMBL8806058 | 0.84 | ABCB1 (0.43) | ABCB1ABCG2TP53RXFP1LMNA | |
| SCHEMBL8806985 | 0.84 | ABCB1 (0.42) | ABCB1ABCG2MAPTTP53RXFP1 | |
| SCHEMBL8807343 | 0.83 | ABCB1 (0.42) | ABCB1ABCG2MAPTTP53RXFP1 | |
| SCHEMBL8808244 | 0.83 | MAPT (0.39) | SLC2A1ABCG2MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |