Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805405 | 0.86 | MAPT (0.54) | NTRK1RAB9APOLBMEN1KMT2A | |
| SCHEMBL8807102 | 0.84 | AKR1C2 (0.63) | NTRK1POLBMEN1KMT2AMAPT | |
| SCHEMBL8806561 | 0.81 | SIRT1 (0.56) | NTRK1RAB9ANPC1POLBMEN1 | |
| SCHEMBL1757962 | 0.77 | KDM4E (0.73) | POLBPRSS1PRSS2PRSS3KLK6 | |
| SCHEMBL1757929 | 0.76 | AKR1C2 (0.54) | POLBPRSS1PRSS2PRSS3KLK6 | |
| SCHEMBL8804504 | 0.76 | NPC1 (0.54) | NTRK1RAB9ANPC1TSHRMAPT | |
| SCHEMBL5210674 | 0.76 | MAPT (0.54) | NTRK1POLBPRSS1PRSS2PRSS3 | |
| SCHEMBL8296306 | 0.73 | PRSS1 (0.55) | PRSS1PRSS2PRSS3KLK6MEN1 | |
| SCHEMBL3306868 | 0.71 | MEN1 (0.68) | POLBMEN1KMT2ATSHRMAPT | |
| SCHEMBL8806089 | 0.71 | CNR1 (0.45) | RAB9ANPC1EPHB2ALDH1A1SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |