⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9326433 | 0.99 | — | — | |
| SCHEMBL9324400 | 0.87 | — | — | |
| SCHEMBL9325751 | 0.84 | — | — | |
| SCHEMBL3549920 | 0.82 | — | — | |
| SCHEMBL8806239 | 0.82 | — | — | |
| Water SCHEMBL10644392 | 0.81 | — | — | |
| Water SCHEMBL10644904 | 0.81 | — | — | |
| Water SCHEMBL10643662 | 0.81 | — | — | |
| SCHEMBL10468445 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL9326121 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321186-A1 | 6-(Substituted methylene)penems | BEECHAM GROUP PLC (GB) | 1989-06-21 | — | — | EP | claimed |
| EP-0321186-B1 | 6-(Substituted methylene)penems | BEECHAM GROUP PLC (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0321187-B1 | 6-(SUBSTITUTED METHYLENE)PENEMS | BEECHAM GROUP PLC (GB) | 1993-07-28 | — | — | EP | disclosed |
| US-4931434-A | Penem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-06-05 | — | — | US | disclosed |
| US-4923856-A | Penem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-05-08 | — | — | US | disclosed |
| EP-0321186-A1 | 6-(Substituted methylene)penems | BEECHAM GROUP PLC (GB) | 1989-06-21 | — | — | EP | disclosed |
| EP-0321187-A1 | 6-(Substituted methylene)penems | BEECHAM GROUP PLC (GB) | 1989-06-21 | — | — | EP | disclosed |