Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 12/20 | 1.00 |
| ▸ | AR | P10275 | 9/20 | 1.00 |
| ▸ | ESR1 | P03372 | 3/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806499 | 1.00 | PGR (1.00) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL8806388 | 0.94 | PGR (0.88) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL8808541 | 0.86 | PGR (1.00) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL4176522 | 0.84 | NR3C1 (1.00) | PGRNR3C1AR | |
| SCHEMBL8141286 | 0.83 | NR3C1 (1.00) | PGRNR3C1AR | |
| SCHEMBL8148258 | 0.81 | PGR (1.00) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL6294344 | 0.80 | NR3C1 (0.74) | PGRNR3C1AR | |
| SCHEMBL4176184 | 0.79 | NR3C1 (0.75) | PGRNR3C1AR | |
| SCHEMBL5355526 | 0.79 | PGR (0.75) | PGRNR3C1ARNR3C2 | |
| SCHEMBL4170287 | 0.78 | NR3C1 (0.89) | PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800519-A1 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996019458-A2 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-06-27 | — | — | WO | disclosed |