Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809895 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8807672 | 0.98 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8806535 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8809207 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8806711 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8807035 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8807846 | 0.83 | ACHE (0.48) | KDM4EHPGDMAPTMEN1KMT2A | |
| SCHEMBL8806057 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8806039 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL8807799 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584091-B1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-5428038-A | Administering for preventing or treating N-methyl-D-aspartate induced convulsions | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0584091-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF. | SCHWABE WILLMAR GMBH & CO (DE) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018493-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1992-10-29 | — | — | WO | disclosed |