Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | CASP1 | P29466 | 6/20 | 0.61 |
| ▸ | CASP7 | P55210 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.61 |
| ▸ | GLA | P06280 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807348 | 0.80 | CA9 (0.46) | KDM4EALDH1A1HPGDCASP1CASP7 | |
| SCHEMBL16674816 | 0.77 | MAOA (0.68) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL8809491 | 0.76 | MAOB (0.55) | KDM4ECA12CA9MEN1KMT2A | |
| Scopoletin SCHEMBL147702 | 0.76 | CA9 (1.00) | KDM4EALDH1A1HPGDCASP1CASP7 | |
| Scopoletin SCHEMBL21114360 | 0.76 | CA9 (1.00) | KDM4EALDH1A1HPGDCASP1CASP7 | |
| SCHEMBL22273624 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1HPGDCASP1CASP7 | |
| Scopoletin SCHEMBL29712325 | 0.76 | CA9 (1.00) | KDM4EALDH1A1HPGDCASP1CASP7 | |
| 7-Cyclohexyloxycoumarin SCHEMBL14802688 | 0.75 | MAOA (0.67) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL28918559 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL8808950 | 0.74 | MCL1 (0.42) | KDM4EALDH1A1HPGDCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584091-B1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-5428038-A | Administering for preventing or treating N-methyl-D-aspartate induced convulsions | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0584091-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF. | SCHWABE WILLMAR GMBH & CO (DE) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018493-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1992-10-29 | — | — | WO | disclosed |